id,value,what_it_measures,sample,method,source_org,year,live_url,tier,self_reported_or_independent,used_in_summary_table,note
M01,"361 randomized (181 IPM plus education, 180 education alone); 334 in primary analysis",Trial size,"Mouse-sensitized, mouse-exposed children aged 5-17 with asthma, Baltimore and Boston","Randomized clinical trial, enrollment May 2010 to Aug 2014, 12-month follow-up","Matsui et al. (Johns Hopkins, Columbia, Boston Children's), JAMA",2017,https://jamanetwork.com/journals/jama/fullarticle/2607513,1,INDEPENDENT,Y,Full text via NCBI PMC5632564
M02,Median maximal symptom days per 2 weeks: 2.0 (IQR 0.7-4.7) IPM plus education vs 2.7 (IQR 1.3-5.0) education alone; P = .16; ratio 0.86 (95% CI 0.69-1.06),"Primary outcome: highest of 3 symptom-day counts over 6, 9 and 12 months",334 analyzed,Participant-reported symptom diaries in an unblinded trial,"Matsui et al. (Johns Hopkins, Columbia, Boston Children's), JAMA",2017,https://jamanetwork.com/journals/jama/fullarticle/2607513,1,SELF-REPORTED,Y,No statistically significant difference
M03,Bedroom floor Mus m 1 geometric mean at baseline: 6.1 ug/g (IPM) vs 6.6 ug/g (education),Baseline allergen,174 IPM and 172 education bedrooms (Table 1),Dust vacuumed and assayed by lab,"Matsui et al. (Johns Hopkins, Columbia, Boston Children's), JAMA",2017,https://jamanetwork.com/journals/jama/fullarticle/2607513,1,INDEPENDENT,Y,
M04,Bedroom floor Mus m 1 across follow-up: 2.0 ug/g (95% CI 1.6-2.5) IPM vs 2.5 ug/g (95% CI 2.0-3.3) education; difference -0.42 (95% CI -0.91 to 0.07),Allergen after intervention,174 IPM and 172 education bedrooms,"Lab-assayed dust at 6, 9 and 12 months","Matsui et al. (Johns Hopkins, Columbia, Boston Children's), JAMA",2017,https://jamanetwork.com/journals/jama/fullarticle/2607513,1,INDEPENDENT,Y,Not statistically different between arms
M05,"Bedroom floor allergen fell at least 50% at any follow-up in 83% (144/174) IPM vs 80% (137/172) education, P = .55; at least 75% in 63% vs 58%, P = .45; at least 90% in 46% vs 41%, P = .44",Share of homes with large allergen drops,346 bedrooms,Prespecified reduction thresholds,"Matsui et al. (Johns Hopkins, Columbia, Boston Children's), JAMA",2017,https://jamanetwork.com/journals/jama/fullarticle/2607513,1,INDEPENDENT,Y,Education-only arm also cut allergen sharply
M06,"Airborne Mus m 1 2.19 pg/m3 (IPM) vs 4.68 pg/m3 (education), difference -1.08 (95% CI -1.51 to -0.65); bed dust 0.58 vs 0.75 ug/g, difference -0.43 (95% CI -0.84 to -0.02)",Secondary allergen measures,155 and 156 air samples; 174 and 172 bed dust samples,Lab-assayed air and dust,"Matsui et al. (Johns Hopkins, Columbia, Boston Children's), JAMA",2017,https://jamanetwork.com/journals/jama/fullarticle/2607513,1,INDEPENDENT,Y,Air and bed dust differed significantly
M07,A 90% drop in bedroom floor allergen was estimated to mean 14.1 fewer maximal symptom days per year (P < .001),"Modeled exposure-response inside the trial, not a group comparison",Both arms pooled,Random-effects models on repeated measures,"Matsui et al. (Johns Hopkins, Columbia, Boston Children's), JAMA",2017,https://jamanetwork.com/journals/jama/fullarticle/2607513,1,SELF-REPORTED,Y,Symptom outcome is self-reported; estimate is observational within the trial
M08,"IPM visits delivered: 1 visit 18%, 2 visits 28%, 3 visits 24%, 4 visits 30%; 290 of 311 indicated treatments (93%) delivered",Intervention intensity,181 IPM households,Trial records,"Matsui et al. (Johns Hopkins, Columbia, Boston Children's), JAMA",2017,https://jamanetwork.com/journals/jama/fullarticle/2607513,1,INDEPENDENT,Y,"Treatments: rodenticide, sealing, traps, cleaning, mattress and pillow covers, air purifiers"
M09,11% of the education-only group hired an exterminator by 6 months and 8% by 12 months,Cross-over to professional service,172 to 180 education-only households,Participant report,"Matsui et al. (Johns Hopkins, Columbia, Boston Children's), JAMA",2017,https://jamanetwork.com/journals/jama/fullarticle/2607513,1,SELF-REPORTED,Y,No arm received zero pest advice
M10,Trial sized for 90% power to detect a 0.7-day difference in maximal symptom days per 2 weeks (150 per group planned),Design assumption,300 planned,Sample size calculation,"Matsui et al. (Johns Hopkins, Columbia, Boston Children's), JAMA",2017,https://jamanetwork.com/journals/jama/fullarticle/2607513,1,INDEPENDENT,Y,
M11,"Household income under $30,000: 113 of 174 (64%) in the IPM arm and 119 of 172 (68%) in the education arm",Trial population income,346 analyzed households,Baseline table,"Matsui et al. (Johns Hopkins, Columbia, Boston Children's), JAMA",2017,https://jamanetwork.com/journals/jama/fullarticle/2607513,1,SELF-REPORTED,N,Context for who was studied
P01,12 intervention and 6 control homes randomized 2:1; 5-month follow-up,Pilot size,18 Boston homes of children with mouse skin-test positive asthma,"Randomized pilot: copper mesh, cleaning, low-toxicity pesticides, traps","Phipatanakul et al. (Boston Children's Hospital), Ann Allergy Asthma Immunol",2004,https://pubmed.ncbi.nlm.nih.gov/15104193/,1,INDEPENDENT,Y,Abstract reports allergen outcomes only
P02,Mouse allergen at month 5: kitchen -78.8% vs +319% control (P = .02); bedroom -77.3% vs +358% (P < .01); living room -67.6% vs -32% (P = .07),Change in Mus m 1 from baseline,"12 intervention, 6 control","Lab-assayed dust at baseline, 1, 3 and 5 months","Phipatanakul et al. (Boston Children's Hospital), Ann Allergy Asthma Immunol",2004,https://pubmed.ncbi.nlm.nih.gov/15104193/,1,INDEPENDENT,Y,Very small trial
G01,Bedroom floor Mus m 1 fell 27.3% (95% CI -46.1% to -1.9%) in 150 homes given a rodent-specific intervention,Allergen change after intervention,150 intervention homes (Inner-City Asthma Study subanalysis),Bedroom dust assayed for Mus m 1 every 6 months for 2 years,"Pongracic et al. (Inner-City Asthma Study), Ann Allergy Asthma Immunol",2008,https://pubmed.ncbi.nlm.nih.gov/18681082/,1,INDEPENDENT,Y,
G02,22% of children skin-tested positive to mouse; 80% of bedrooms had detectable Mus m 1,Prevalence in inner-city asthma cohort,"Children aged 5 to 11 with asthma, 7 US cities",Skin test and dust assay,"Pongracic et al. (Inner-City Asthma Study), Ann Allergy Asthma Immunol",2008,https://pubmed.ncbi.nlm.nih.gov/18681082/,1,INDEPENDENT,Y,
G03,"Allergen reduction was associated with less missed school, sleep disruption and caretaker burden, but not symptoms or medical use",Association with morbidity,150 intervention homes,Caregiver-reported outcomes,"Pongracic et al. (Inner-City Asthma Study), Ann Allergy Asthma Immunol",2008,https://pubmed.ncbi.nlm.nih.gov/18681082/,1,SELF-REPORTED,Y,"Association, not a control comparison"
N01,"937 children aged 5-11 in 7 cities: symptom days per 2 weeks 3.39 (intervention) vs 4.20 (control) during the intervention year, P < .001; 2.62 vs 3.21 the next year, P < .001",Symptom days with a multi-trigger home intervention,937 children with atopic asthma,Randomized trial; education and remediation for allergens and tobacco smoke,"Morgan et al. (Inner-City Asthma Study Group), N Engl J Med",2004,https://www.nejm.org/doi/full/10.1056/NEJMoa032097,1,SELF-REPORTED,Y,"Abstract credits cockroach and dust mite allergen drops, not mouse"
K01,280 apartments in 13 buildings across 5 NYC public housing developments; single IPM visit averaging 2-3 hours,Trial size and intensity,Brooklyn and Manhattan public housing,"Building-level assignment, baseline, 3 and 6 months","Kass et al. (NYC Dept of Health and Mental Hygiene), Environ Health Perspect",2009,https://pmc.ncbi.nlm.nih.gov/articles/PMC2721864/,1,INDEPENDENT,Y,Cockroach-focused study
K02,"Mouse allergen IPM:control ratio at 6 months: kitchen 0.7 (95% CI 0.4-1.4), bedroom 0.8 (95% CI 0.6-1.1); not significant",Mouse urinary protein in dust,280 apartments,"Lab-assayed dust, models adjusted for baseline","Kass et al. (NYC Dept of Health and Mental Hygiene), Environ Health Perspect",2009,https://pmc.ncbi.nlm.nih.gov/articles/PMC2721864/,1,INDEPENDENT,Y,Authors cite low mouse prevalence
K03,"Cockroach allergen Bla g 2 IPM:control ratio at 6 months: kitchen 0.3 (95% CI 0.1-0.9), bedroom 0.4 (95% CI 0.2-0.8)",Contrast with cockroach allergen,280 apartments,Lab-assayed dust,"Kass et al. (NYC Dept of Health and Mental Hygiene), Environ Health Perspect",2009,https://pmc.ncbi.nlm.nih.gov/articles/PMC2721864/,1,INDEPENDENT,N,Context only
S01,"18 buildings in 3 New Jersey cities randomized to trap and bait, trap bait and exclusion, or existing pest control; 10 infested apartments per arm per city sampled",Trial design,"Public housing apartments, New Brunswick, Trenton, Paterson","Dust from kitchen, bedroom and bed at baseline, 6 months and 12 or 24 months","Sarker et al. (Rutgers, Johns Hopkins), J Allergy Clin Immunol Glob",2025,https://pubmed.ncbi.nlm.nih.gov/40895412/,1,INDEPENDENT,Y,Funded by HUD and USDA-NIFA; authors declare no conflicts
S02,"Kitchen Mus m 1 fell 97.4% (New Brunswick, 24 months), 85.8% (Trenton, 24 months) and 34.9% (Paterson, 12 months) in treated buildings",Change in kitchen allergen,10 infested apartments per arm per city,Mus m 1 by monoclonal ELISA at Johns Hopkins lab,"Sarker et al. (Rutgers, Johns Hopkins), J Allergy Clin Immunol Glob",2025,https://pubmed.ncbi.nlm.nih.gov/40895412/,1,INDEPENDENT,Y,Verified in full text; abstract omits the time points
S03,"Control kitchens changed by -61.4% (New Brunswick), +671.4% (Trenton) and +289.6% (Paterson); a minus sign is a reduction",Change in kitchen allergen with conventional pest control,Control arm apartments,Same assay,"Sarker et al. (Rutgers, Johns Hopkins), J Allergy Clin Immunol Glob",2025,https://pubmed.ncbi.nlm.nih.gov/40895412/,1,INDEPENDENT,Y,Percent changes swing widely on small bases
S04,No significant bedroom reduction in treated buildings versus control in any of the 3 cities,Bedroom allergen,Bedroom or bed samples,Same assay,"Sarker et al. (Rutgers, Johns Hopkins), J Allergy Clin Immunol Glob",2025,https://pubmed.ncbi.nlm.nih.gov/40895412/,1,INDEPENDENT,Y,
S05,Trap-and-bait and trap-bait-exclusion arms showed no difference in mouse infestation rates after intervention,Effect of adding exclusion,Both treated arms,"Building inspections at 6, 12 and 24 months","Sarker et al. (Rutgers, Johns Hopkins), J Allergy Clin Immunol Glob",2025,https://pubmed.ncbi.nlm.nih.gov/40895412/,1,INDEPENDENT,Y,Only direct exclusion comparison found
S06,New Brunswick kitchen Mus m 1 fell 58.0% from 0 to 6 months in treated buildings versus a 396.1% rise in control (P = .007),Early allergen change,New Brunswick apartments,Same assay; 6-month samples taken Dec-Jan,"Sarker et al. (Rutgers, Johns Hopkins), J Allergy Clin Immunol Glob",2025,https://pubmed.ncbi.nlm.nih.gov/40895412/,1,INDEPENDENT,Y,Seasonal variation noted by authors
S07,"Authors flag small sample counts at 12 months (type II error risk), large baseline variance and natural fluctuation as limits",Limitation,Paterson and control arms,Author discussion,"Sarker et al. (Rutgers, Johns Hopkins), J Allergy Clin Immunol Glob",2025,https://pubmed.ncbi.nlm.nih.gov/40895412/,1,INDEPENDENT,N,
D01,Building-wide mouse programs cut infested apartments 87% on average at 3 months; at 12 months infestations fell 94% in one building and rose 26% in the other,Mouse infestation counts,"2 New Jersey high-rise buildings, 2019-2020",Bait-station monitoring; rodenticides applied over 63 days then returned to contractors,"Sked et al. (Rutgers), Animals",2021,https://pubmed.ncbi.nlm.nih.gov/33804552/,1,INDEPENDENT,Y,Tiny sample
O01,384 children aged 5-12 with persistent asthma and a pest infestation; 183 assigned to one-time IPM and 197 to usual care,Trial size,NYC households,"Randomized trial, one-time apartment-level IPM","Olson et al. (NYC Dept of Health and Mental Hygiene), J Asthma",2021,https://pubmed.ncbi.nlm.nih.gov/31920176/,1,INDEPENDENT,Y,"Abstract group counts sum to 380, not 384"
O02,Health-care use declined equally in both arms (primary outcome),Hospital and Medicaid claims,IPM and usual care groups,Administrative records,"Olson et al. (NYC Dept of Health and Mental Hygiene), J Asthma",2021,https://pubmed.ncbi.nlm.nih.gov/31920176/,1,INDEPENDENT,Y,
O03,"Fewer days with reduced activity in IPM (P = 0.04); symptom days P = 0.22, severe symptoms P = 0.16, missed school P = 0.27, rescue medication P = 0.27; roach infestation P = 0.001, mouse infestation P = 0.11",Caregiver-reported secondary outcomes and infestation,IPM and usual care groups,Caregiver questionnaires and pest monitoring,"Olson et al. (NYC Dept of Health and Mental Hygiene), J Asthma",2021,https://pubmed.ncbi.nlm.nih.gov/31920176/,1,SELF-REPORTED,Y,One of 5 symptom-type outcomes significant
C01,236 students at 41 urban elementary schools; mean age 8.1; 98% of classrooms had detectable mouse allergen at baseline,Trial size and exposure,"Northeastern US schools; blinded, sham-controlled","Factorial RCT of school IPM and classroom HEPA filters, 2015-2020","Phipatanakul et al. (School Inner-City Asthma Intervention Study), JAMA",2021,https://pubmed.ncbi.nlm.nih.gov/34547084/,1,INDEPENDENT,Y,
C02,"Symptom days per 2 weeks: 1.5 (school IPM) vs 1.9 (no IPM), incidence rate ratio 0.71 (95% CI 0.38-1.33); HEPA 1.6 vs 1.8, ratio 1.47 (95% CI 0.79-2.75)",Primary outcome: asthma symptom-days,All 236 completed,Reported symptom-days every 2 months for 10 months,"Phipatanakul et al. (School Inner-City Asthma Intervention Study), JAMA",2021,https://pubmed.ncbi.nlm.nih.gov/34547084/,1,SELF-REPORTED,Y,Not statistically significant
C03,"School IPM cost $7.27 per student; IPM plus HEPA cost $12.21 per student and $19,667 per QALY",School-level cost,"154 SICAS2 participants, 2021 dollars","Cost-effectiveness analysis, mean follow-up 166 days","Socolovsky et al. (Harvard, Boston Children's), Allergy Asthma Proc",2025,https://pubmed.ncbi.nlm.nih.gov/40380354/,1,INDEPENDENT,N,"School setting, not homes"
C04,"A classroom microbiome signature of IPM linked to lower odds of any asthma symptom day (OR 0.47, 95% CI 0.22-0.97), adjusting for mouse allergen",Ancillary association,"208 classrooms, 41 schools",Metagenomic sequencing of dust; observational within trial,"Kim et al. (Massachusetts General Hospital, Harvard), J Allergy Clin Immunol",2026,https://pubmed.ncbi.nlm.nih.gov/42617883/,1,SELF-REPORTED,N,Online ahead of print Aug 2026; association only
V01,Detectable Mus m 1 in 82% of US homes,Prevalence of mouse allergen,"831 US housing units, national sample",National Survey of Lead and Allergens in Housing,"Cohn et al. (NIEHS, National Survey of Lead and Allergens in Housing), J Allergy Clin Immunol",2004,https://pubmed.ncbi.nlm.nih.gov/15208600/,1,INDEPENDENT,Y,Dust assay
V02,Kitchen Mus m 1 above 1.6 ug/g in 22% of homes; odds 3.38 with reported rodent problems and 2.17 when floors were mopped instead of vacuumed,Elevated exposure and risk factors,831 homes,Cross-sectional survey,"Cohn et al. (NIEHS, National Survey of Lead and Allergens in Housing), J Allergy Clin Immunol",2004,https://pubmed.ncbi.nlm.nih.gov/15208600/,1,INDEPENDENT,Y,
V03,"Mouse urinary protein above 1.6 ug/g in 35% of homes; in allergic residents, adjusted odds of asthma symptoms 1.93 (95% CI 1.14-3.27)",Exposure and asthma symptom odds,"831 homes, 2,456 people",Cross-sectional; symptoms by questionnaire,"Salo et al. (NIEHS), Environ Health Perspect",2009,https://pubmed.ncbi.nlm.nih.gov/19337513/,1,SELF-REPORTED,Y,"Association, not causation"
V04,41% of 144 Baltimore children with asthma were mouse sensitized and exposed; mouse allergen tracked worse outcomes more consistently than cockroach,Local sensitization,144 children aged 5-17,"Skin tests, dust assays, clinical data over 12 months","Ahluwalia et al. (Johns Hopkins), J Allergy Clin Immunol",2013,https://pubmed.ncbi.nlm.nih.gov/23810154/,1,INDEPENDENT,Y,
V05,18% of 499 children had a positive mouse skin test; sensitization 23% vs 11% with kitchen allergen above the 1.60 ug/g median (P = .007); link to asthma morbidity not significant,Sensitization and exposure,"499 children, National Cooperative Inner-City Asthma Study",Skin test and dust assay,"Phipatanakul et al. (National Cooperative Inner-City Asthma Study), J Allergy Clin Immunol",2000,https://pubmed.ncbi.nlm.nih.gov/11112889/,1,INDEPENDENT,Y,
V06,Mice found in 13% and cockroaches in 77% of 324 NYC public housing apartments; high mouse allergen linked to 6.6-fold odds of an asthmatic resident in senior buildings (95% CI 1.4-31.7),Pest and allergen prevalence,324 apartments,"Pest monitoring, dust assay, resident interviews","Chew et al. (Columbia), Ann Allergy Asthma Immunol",2006,https://pubmed.ncbi.nlm.nih.gov/17069106/,1,INDEPENDENT,Y,
V07,"24% of occupied NYC units (766,700, margin of error 25,530) reported rodents in the building in 2021","Rodent presence, species not specified",NYC occupied housing units,US Census Bureau survey for NYC HPD,"US Census Bureau and NYC Dept of Housing Preservation and Development, NYC Housing and Vacancy Survey",2021,https://www.nyc.gov/assets/hpd/downloads/pdfs/services/2021-nychvs-selected-initial-findings.pdf,1,SELF-REPORTED,Y,Rats and mice not separated
V08,"81% of 358 Gary, Indiana public housing apartments had a pest infestation; diagnosed asthma correlated with mouse infestation",Infestation and asthma link,"358 apartments, 1,173 residents",Interviews and inspection,"Wang et al. (Purdue), J Community Health",2008,https://pubmed.ncbi.nlm.nih.gov/18080206/,1,SELF-REPORTED,N,"Midwest, used in text only"
V09,"Persistent asthma emergency-department hot spots detected in Westchester County near Yonkers in 2016-2019, with more zip codes flagged during 2020-2022",Asthma ED visits by zip code,New York State zip codes,Emerging hot spot analysis of quarterly ED visit rates,"CDC, Preventing Chronic Disease",2024,https://www.cdc.gov/pcd/issues/2024/24_0059a.htm,1,INDEPENDENT,Y,Asthma proxy only. No mouse allergen data for Westchester
W01,"For asthma with pest sensitization or symptoms, IPM alone or within a multicomponent plan is conditionally recommended; certainty of evidence low (Recommendation 7)",Guideline strength,Expert Panel review of the evidence,Systematic review and GRADE process,"NHLBI National Asthma Education and Prevention Program Expert Panel (Cloutier et al.), J Allergy Clin Immunol",2020,https://pmc.ncbi.nlm.nih.gov/articles/PMC7924476/,2,INDEPENDENT,Y,
W02,59 randomized and 8 non-randomized trials of 8 indoor allergen interventions; pest control inside multicomponent studies reduced exacerbations (moderate certainty) and improved quality of life (low certainty),Systematic review of allergen reduction,67 studies,Cochrane risk-of-bias and AHRQ evidence grading,"Leas et al. (Penn Medicine and ECRI), J Allergy Clin Immunol",2018,https://pubmed.ncbi.nlm.nih.gov/29452202/,2,INDEPENDENT,Y,Single-intervention pest control studies were too few to judge
W03,Pest control inside multicomponent studies did not reduce emergency department visits (moderate certainty) or hospitalizations (high certainty); it cut school absenteeism (low certainty),AHRQ report detail,Same review,Strength-of-evidence grading,Leas et al. (AHRQ Comparative Effectiveness Review 18-EHC002-EF),2018,https://pubmed.ncbi.nlm.nih.gov/29708676/,2,INDEPENDENT,Y,"Same review as W02, separate publisher"
W04,54 randomized trials of home interventions for childhood asthma; 4 targeted pest allergen; only 3 studies were high quality; no clear effect for pest interventions,Systematic review 2025,"54 RCTs from 13,124 records",GRADE and Cochrane risk of bias,"Hogaard et al. (Aarhus University Hospital), Respir Med",2025,https://pubmed.ncbi.nlm.nih.gov/40774466/,2,INDEPENDENT,Y,
W05,"CDC advises sealing cracks, storing food airtight and removing water and food sources for pests, and says to avoid sprays and foggers because they can cause asthma attacks",Agency guidance,n/a,Public guidance page,"Centers for Disease Control and Prevention, Controlling Asthma",n.d. (accessed 2026-09-28),https://www.cdc.gov/asthma/control/index.html,2,INDEPENDENT,Y,
W06,"EPA lists pest droppings and body parts as asthma triggers, advises non-chemical steps such as cleaning and sealing, and warns that pesticides can harm people",Agency guidance,n/a,Public guidance page,"US Environmental Protection Agency, Asthma Triggers: Gain Control",n.d. (accessed 2026-09-28),https://www.epa.gov/asthma/asthma-triggers-gain-control,2,INDEPENDENT,Y,Paraphrased
X01,0 of 3 mouse-focused pest control RCTs reached P < .05 on a primary symptom or care-use outcome,Derived count,"Matsui 2017 (M02), Olson 2021 (O02), Phipatanakul 2021 (C02)",Count of trials with a significant primary symptom or care-use result,Pristine Pest calculation from cited rows,2026,https://pestcontrolscarsdale.com/blog/mouse-control-asthma-allergen-evidence/,derived,INDEPENDENT,N,Own calculation
X02,981 children and students in those 3 trials,Derived sum,361 + 384 + 236,Addition of published enrollment,Pristine Pest calculation from cited rows,2026,https://pestcontrolscarsdale.com/blog/mouse-control-asthma-allergen-evidence/,derived,INDEPENDENT,N,Own calculation. Olson enrollment as stated in abstract
X03,2 of 2 trials built to test allergen reduction found a significant kitchen drop versus control,Derived count,Phipatanakul 2004 (P02) and Sarker 2025 (S02),Count of allergen-primary trials with P < .05,Pristine Pest calculation from cited rows,2026,https://pestcontrolscarsdale.com/blog/mouse-control-asthma-allergen-evidence/,derived,INDEPENDENT,N,Own calculation